CUPE represents over 200,000 health care workers from coast to coast. Approximately 190,000 of those members work in dedicated health care locals such as hospitals, long-term care, community and public health, home care, and at Canadian Blood Services and Héma-Québec. The remaining members work primarily in the Municipal and Social Services sectors.

CUPE represents health care workers in every province, with the largest numbers in Ontario (Ontario Council of Hospital Unions members), British Columbia (Hospital Employees’ Union members), Quebec (through the Conseil provincial des affaires sociales), Manitoba, Saskatchewan, and New Brunswick.